I personally use the Canon 200EG that is made of rugged nylon holds up to 2 camera bodies, 4 lenses, plus accessories. If you want to see what I load up in mine, go to:
http://www.agentz.com/CanonPhotoBackpack/

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Product Details

• Brand: Canon

Features

• Store, carry, and protect your camera equipment
• Waterproofed backpack
• 2 foam-padded main sections
• Constructed out of durable materials
• Adjustable waist belt

Amazon.com Product Description
For the adventurous photographer, the Canon Deluxe Back Pack 10 holds up to two camera bodies and five lenses within its two foam-padded main sections, and its zippered pouches provide plenty of room for media and batteries. The waterproofed backpack protects your camera equipment from the ravages of dirt and water, and sits securely on your shoulders, with a waist belt for added comfort.

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Customer Reviews

Canon Deluxe Back Pack 10
The Canon Deluxe Back Pack 10 is very practical. First off it's waterproof. It holds 1-2 cameras and 4-6 lenses and a wide range of accesories which should be enough for any photographer. It is very padded for comfort. Has a tripod holder. Adjustable waist belt which prevents the backpack from bouncing. Great for nature photographers. Very light and compact. If the Deluxe Back Pack 10 is to small, Canon makes the Profesional Back Pack 1 which is just a larger version. This backpack is also very stylish.