Product Description

This report summarizes the scientific literature on 12 of the 35 pesticides that are likely to have been used during the Persian Gulf War. Where possible, it focuses on known pesticide exposures or doses and related health outcomes that may be relevant to symptoms reported by some Gulf War veterans. Particular attention is paid to long-term, chronic effects of reported exposures to organophosphate and carbamate pesticides.Evidence from epidemiological studies, studies of genetic and biological differences between ill and healthy subjects, and studies of the physiological mechanisms of organophosphate and carbamate pesticides is suggestive, but not conclusive, that these pesticides could be among the potential contributing agents to some of the undiagnosed illnesses seen in Gulf War veterans. However, no prospective studies have been conductedthat positively identify pesticides as causative agents. More research is needed to confirm or refute a causal link between pesticides and other agents and the symptoms associated with Gulf War illnesses.

Product Details

• Amazon Sales Rank: #4539895 in Books
• Published on: 2001-02-25
• Original language: English
• Number of items: 1
• Binding: Paperback
• 216 pages

From the Publisher
Veterans of the Persian Gulf War report a variety of physical and psychological symptoms, some of which remain unexplained.In an effort to determine the extent to which these symptoms may be related to Gulf War service and to develop policies tobetter deal with health risks in future deployments, the Secretary of Defense designated a special assistant to oversee allDepartment of Defense (DoD) efforts related to the illnesses of Gulf War veterans. The Office of the Special Assistant for GulfWar Illnesses (OSAGWI) is charged to do everything possible to understand and explain the illnesses, to inform veterans andthe public of its progress and findings, and to recommend changes in DoD policies and procedures to minimize such problemsin the future. This literature review, one of eight commissioned by the Special Assistant to the Deputy Secretary of Defense for Gulf WarIllnesses, summarizes the existing scientific literature on the health effects of the classes of pesticides that may have affectedmilitary personnel who served in Operations Desert Shield and Desert Storm (ODS/DS). The eight RAND reviews areintended to complement efforts by the DoD and other federal agencies to understand the full range of health implications ofservice in that conflict. The other seven RAND literature reviews deal with chemical and biological warfare agents, depleted uranium, oil well fires,pyridostigmine bromide, immunizations, infectious diseases, and stress. These represent plausible causes of some of the illnessesGulf War veterans have reported. The reviews are intended principally to summarize the scientific literature on the known health effects of given exposures tothese risk factors. Where available evidence permits, the other seven reviews also summarize what is known about the range ofactual exposures in the Gulf War and assess the plausibility of each risk factor as a cause of illness. A RAND reportcomplementary to this review examines the exposure of Gulf War veterans to pesticides through an extensive survey;[1]consequently, this review does not detail the actual range of pesticide exposures during ODS/DS. Statements related to theGulf War experience should be regarded as suggestive rather than definitive, for more research on health effects and exposuresremains to be completed before definitive statements can be made. Recommendations for additional research are includedwhere appropriate. The RAND reviews are limited to literature published or accepted for publication in peer-reviewed journals, books,government publications, and conference proceedings. Unpublished information is occasionally used, but only to develophypotheses. The present review uses literature published before completion of the initial draft, but some additional referenceshave been included, primarily in response to peer review. This work is sponsored by the Office of the Special Assistant and was carried out jointly by RAND Health's Center forMilitary Health Policy Research and the Forces and Resources Policy Center of the National Defense Research Institute. Thelatter is a federally funded research and development center sponsored by the Office of the Secretary of Defense, the JointStaff, the unified commands, and the defense agencies.

About the Author
Beatrice Alexandra Golomb (PhD, Biology, University of California, San Diego, June, 1988MD, University of California, San Diego, June, 1989) is a Health Consultant at RAND.

Customer Reviews

THE FIRST AUTHOR IS GARY CECCHINE, NOT B. GOLOMB
Click on the thumbnail to see a larger picture of the book - see what I mean?

Well balanced, insightful review.