Listmania!
Great DS Games for Kids
By an Amazon.com customer
Smart Girls: PlayhouseSmart Girls: Playhouse
Buy new: $19.99 / Used from: $34.99
You don't need to read for this game. Lots of activities for younger girls to do. There other games in this series that are also good.
Smart Boy's: Toy ClubSmart Boy's: Toy Club
Buy used from: $18.99
You don't need to read for this game. Lots of activities for younger boys to do. There are other games in this series that are also good.
Crayola Treasure AdventuresCrayola Treasure Adventures
Buy new: $34.98 / Used from: $25.99
If your kid loves coloring buy this! They don't need to know how to read, but you'll have to help them at the beginning so they know what does what.
Build-A-Bear WorkshopBuild-A-Bear Workshop
Buy new: $14.99 / Used from: $12.99
Does not require reading (but they will need some initial help). You can make your own bear and play with it.
Go Diego Go: Safari RescueGo Diego Go: Safari Rescue
Buy new: $13.79 / Used from: $22.18
Don't need to know how to read, but might need your help initially.
Disney Princess: Magical JewelsDisney Princess: Magical Jewels
Buy new: $14.45 / Used from: $12.99
Great for younger girls who can't read. Will need your help initially though.
My Little Pony: Pinkie Pie's PartyMy Little Pony: Pinkie Pie's Party
Buy new: $44.98 / Used from: $25.44
Great for younger girls who can't read. Will need your help initially though.
Littlest Pet Shop: GardenLittlest Pet Shop: Garden
Buy used from: $22.88
There are other versions other than garden. Lots of mini games. Requires some reading. Probably better for ages 6 and up but if you want to help a younger child get the hang of it they will learn where things are eventually and they can play some of the simpler mini games.
Disney Fairies: TinkerbellDisney Fairies: Tinkerbell
Buy new: $19.15 / Used from: $11.49
Haven't played this, but most younger kids seem to enjoy it. They need to know how to read a little though (or they can get help from you).
Nintendogs Labrador Retriever & FriendsNintendogs Labrador Retriever & Friends
Buy new: $27.82 / Used from: $16.99
You can't go wrong with any of the Nintendog games. Great for all ages. Cute virtual puppies. There are multiple versions with different dog breeds, so ask your child which dog breed they like best. Even small children can pet the dog and do some of the simpler interactions.
Over the HedgeOver the Hedge
Buy new: $84.56 / Used from: $8.98
A game based on a movie that is actually good.
Super Princess PeachSuper Princess Peach
Buy new: $101.94 / Used from: $29.95
A cute, girly version of the mario platformer. Should be easier than other platformers, so would be good for younger girls (or boys!) who aren't quite ready for mario or sonic.
Kirby Super Star UltraKirby Super Star Ultra
Buy new: $29.96 / Used from: $13.01
My 7 year old cousin enjoys this game. It is an adventure/platform game.
Kirby Canvas CurseKirby Canvas Curse
Buy new: $99.18 / Used from: $19.89
Another fun kirby platformer, but different in that you use the stylus to control him.
Sonic Rush AdventureSonic Rush Adventure
Buy new: $12.60 / Used from: $11.80
Sonic at his fastest.
Planet Puzzle LeaguePlanet Puzzle League
Buy new: $62.94 / Used from: $23.95
A wonderful puzzle game.
SpectrobesSpectrobes
Buy new: $14.99 / Used from: $4.15
Similar to Pokemon. An adventure game where you collect cool monsters and battle with them. The sequel, Spectrobes: Beyond the Portals, and the Wii version, Spectrobes: Origins, are also great.
Mario Kart DSMario Kart DS
Buy new: $29.96 / Used from: $19.44
An amazing racing game with Nintendo characters. You can race people online too.
New Super Mario Bros.New Super Mario Bros.
Buy new: $32.99 / Used from: $21.78
A fun platformer that young kids can enjoy, but might be too difficult for ages less than 6. Depends on your child's reflexes.
Super Mario 64 DSSuper Mario 64 DS
Buy new: $27.82 / Used from: $19.49
This was one of my favorite games, and now it has extra content. Might be too hard for really young gamers, but 5+ can at least play some of it.
Viva Piñata: Pocket ParadiseViva Piñata: Pocket Paradise
Buy new: $29.99 / Used from: $12.71
A virtual pet game where you collect animals to put in your garden.
LEGO BatmanLEGO Batman
Buy new: $18.36 / Used from: $12.00
If your kid likes LEGO, Batman, or action games in general, they'll love this. The other versions (Star Wars the Complete Saga and Indiana Jones) are also great. Make sure to NOT get Star Wars II the Original Trilogy because it was put together by another company and it pales in comparison to the Complete Saga.
Petz Rescue Endangered ParadisePetz Rescue Endangered Paradise
Buy new: $15.79 / Used from: $10.06
Virtual pet game, but with exploration aspects similar to Zelda. The Petz series in general is pretty good.
Ben 10 Protector of the EarthBen 10 Protector of the Earth
Buy new: $12.99 / Used from: $6.98
If your kid likes the TV series, this would be a good choice.
Drawn to Life: Spongebob Squarepants EditionDrawn to Life: Spongebob Squarepants Edition
Buy used from: $23.99
My 7 year old cousin loves this. You get to draw your own character and items in the world. A fun platform/adventure game. There are other versions, too.
Yu-Gi-Oh! World Championship Tournament 2008Yu-Gi-Oh! World Championship Tournament 2008
Buy new: $123.97 / Used from: $22.94
This series is very popular. The other games are pretty good too.
Club Penguin: Elite Penguin ForceClub Penguin: Elite Penguin Force
Buy new: $29.99 / Used from: $14.00
Very popular series that is related to the online website. You can earn coins while playing on the DS to use or transfer wirelessly to your online account.
The Legend of Zelda:  Phantom HourglassThe Legend of Zelda: Phantom Hourglass
Buy new: $32.99 / Used from: $17.90
I love Zelda, it is a great game. Probably better for older kids since it can be challenging (7+).